Jack D Sobel Selected Research

Fluconazole (Zonal)

1/2022	Vulvovaginal Candidiasis: A Review of the Evidence for the 2021 Centers for Disease Control and Prevention of Sexually Transmitted Infections Treatment Guidelines.
1/2022	Determining Susceptibility in Candida Vaginal Isolates.
1/2022	Phase 2 Randomized Study of Oral Ibrexafungerp Versus Fluconazole in Vulvovaginal Candidiasis.
1/2021	In Vitro pH Activity of Ibrexafungerp against Fluconazole-Susceptible and -Resistant Candida Isolates from Women with Vulvovaginal Candidiasis.
1/2020	Prognosis and Long-Term Outcome of Women With Idiopathic Recurrent Vulvovaginal Candidiasis Caused by Candida albicans.
7/2019	CD101 Topical Compared With Oral Fluconazole for Acute Vulvovaginal Candidiasis: A Randomized Controlled Trial.
10/2018	Long-Term Outcomes of Women With Recurrent Vulvovaginal Candidiasis After a Course of Maintenance Antifungal Therapy.
1/2018	A phase 2, randomized, double-blind, placebo-controlled, dose-ranging study to evaluate the efficacy and safety of orally administered VT-1161 in the treatment of recurrent vulvovaginal candidiasis.
10/2016	A Combination Fluorescence Assay Demonstrates Increased Efflux Pump Activity as a Resistance Mechanism in Azole-Resistant Vaginal Candida albicans Isolates.
12/2012	Fluconazole-resistant Candida albicans vulvovaginitis.

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Jack D Sobel Research Topics

Disease

31	Infections 01/2022 - 01/2002
28	Vulvovaginal Candidiasis 10/2022 - 07/2002
24	Bacterial Vaginosis 12/2021 - 07/2002
12	Vaginitis 01/2022 - 06/2002
12	Candidiasis (Moniliasis) 10/2021 - 07/2003
9	Invasive Candidiasis 01/2019 - 06/2004
6	Candidemia 01/2019 - 06/2004
6	Trichomonas Infections 12/2015 - 05/2007
6	Mycoses (Diseases, Fungus) 06/2008 - 09/2003
5	Invasive Fungal Infections 06/2008 - 08/2004
4	Urinary Tract Infections (Urinary Tract Infection) 01/2016 - 03/2007
4	Cryptococcal Meningitis 07/2010 - 10/2004
3	Coinfection 01/2021 - 04/2011
3	HIV Infections (HIV Infection) 11/2017 - 06/2002
3	Gram-Positive Bacterial Infections 07/2011 - 09/2004
3	Acquired Immunodeficiency Syndrome (AIDS) 07/2010 - 11/2005
3	Fever (Fevers) 02/2010 - 06/2006
2	Spontaneous Abortion (Miscarriage) 01/2022 - 09/2011
2	Sexually Transmitted Diseases (Sexually Transmitted Disease) 01/2021 - 02/2005
2	Dysbiosis 01/2021 - 01/2021
2	Reinfection 07/2019 - 08/2016
2	Neutropenia 03/2012 - 06/2006
2	Diabetes Mellitus 05/2011 - 05/2011
2	Neoplasms (Cancer) 04/2011 - 06/2008
2	Cryptococcosis 02/2010 - 06/2009
2	Renal Insufficiency (Renal Failure) 03/2007 - 08/2004
1	Vulvodynia 01/2019
1	Obesity 10/2018
1	Pyelonephritis 01/2016
1	Bacteremia 01/2016
1	Trichomonas Vaginitis 05/2015
1	Systemic candidiasis 03/2015

Drug/Important Bio-Agent (IBA)

24	Fluconazole (Zonal)FDA LinkGeneric 01/2022 - 11/2002
15	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 09/2004
12	Metronidazole (Metric)FDA LinkGeneric 01/2021 - 05/2006
10	AzolesIBA 10/2022 - 09/2003
9	Pharmaceutical PreparationsIBA 04/2022 - 09/2003
8	Amphotericin B (Amphotericin)FDA LinkGeneric 08/2011 - 09/2003
5	ibrexafungerpIBA 10/2022 - 09/2020
5	Antifungal AgentsIBA 05/2011 - 08/2002
4	boric acid (boron oxide hydroxide)IBA 01/2022 - 11/2003
4	Tinidazole FDA Link 07/2011 - 05/2007
4	Flucytosine (Ancobon)FDA Link 02/2010 - 09/2003
3	Voriconazole (Vfend)FDA LinkGeneric 01/2019 - 09/2003
3	Caspofungin (Cancidas)FDA Link 01/2019 - 03/2007
3	EchinocandinsIBA 01/2017 - 07/2006
3	NitroimidazolesIBA 12/2015 - 12/2011
3	Estrogens (Estrogen)FDA Link 05/2013 - 02/2010
3	Vancomycin FDA LinkGeneric 07/2011 - 09/2004
3	quinupristin-dalfopristin (Synercid)FDA Link 07/2011 - 09/2004
3	Daptomycin FDA Link 07/2011 - 09/2004
3	Anti-Infective Agents (Microbicides)IBA 07/2011 - 09/2004
2	VT-1161IBA 10/2021 - 01/2018
2	ChemokinesIBA 01/2021 - 11/2017
2	RezafunginIBA 07/2019 - 01/2017
2	VaccinesIBA 01/2018 - 11/2017
2	DNA (Deoxyribonucleic Acid)IBA 10/2016 - 06/2011
2	Vaginal Creams, Foams, and Jellies (Vaginal Tablet)IBA 07/2015 - 05/2006
2	Glucose (Dextrose)FDA LinkGeneric 06/2014 - 01/2002
2	Sodium Glutamate (Accent)IBA 05/2014 - 06/2008
2	SteroidsIBA 05/2014 - 04/2011
2	Biological ProductsIBA 01/2014 - 05/2011
2	Oral ContraceptivesIBA 05/2013 - 07/2002
2	Clindamycin (Cleocin)FDA LinkGeneric 03/2012 - 09/2011
2	Oxazolidinones (2 Oxazolidone)IBA 07/2011 - 12/2009
2	TeicoplaninIBA 07/2011 - 12/2009
2	telavancin FDA Link 07/2011 - 12/2009
1	SolutionsIBA 12/2021
1	Proteins (Proteins, Gene)FDA Link 01/2021
1	Galectin 3 (LGALS3)IBA 01/2021
1	Chemokine CCL5IBA 01/2021
1	Galectin 1 (LGALS1)IBA 01/2021
1	Polysaccharides (Glycans)IBA 01/2021
1	Galectins (Galectin)IBA 01/2021
1	dasabuvirIBA 01/2020
1	Amino Acids FDA Link 01/2020
1	NucleotidesIBA 01/2020
1	SofosbuvirIBA 01/2020
1	RNA-Dependent RNA Polymerase (RNA Dependent RNA Polymerase)IBA 01/2020
1	Ribavirin (Virazole)FDA LinkGeneric 01/2020
1	isavuconazoleIBA 01/2019
1	InflammasomesIBA 01/2019
1	LanosterolIBA 01/2018
1	potassium hydroxideIBA 01/2018
1	CytokinesIBA 11/2017
1	ceftazidime drug combination avibactamIBA 01/2016
1	Doripenem FDA Link 01/2016
1	Carbapenems (Carbapenem Antibiotics)IBA 01/2016
1	Nucleic AcidsIBA 12/2015
1	Chemokine ReceptorsIBA 03/2015
1	Interleukin-23 (Interleukin 23)IBA 03/2015
1	Interleukin-22 (IL-22)IBA 03/2015
1	Interleukin-17 (Interleukin 17)IBA 03/2015

Therapy/Procedure

39	Therapeutics 10/2022 - 06/2002
4	Aftercare (After-Treatment) 01/2019 - 03/2007
3	Highly Active Antiretroviral Therapy (HAART) 07/2010 - 07/2003
2	Parenteral Nutrition 05/2014 - 04/2011
1	Antibiotic Prophylaxis 10/2021
1	Drug Therapy (Chemotherapy) 08/2021
1	Duration of Therapy 01/2016